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A new paradigm in medicine — integrating therapeutics and diagnostics for better care

Prometheus is committed to improving lives through the development and commercialization of novel pharmaceutical and diagnostic products that enable physicians to provide greater individualized patient care. Our strategy includes the marketing and delivery of proprietary diagnostic testing services, scientific nutritional solutions and pharmaceutical products. By integrating these, Prometheus believes it can provide physicians with more targeted solutions to optimize care for their patients. Prometheus became a part of Nestlé Health Science in July 2011.

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PERSISTANT
DIARRHEA
PROMETHEUS®

IBcause™
Diagnostic Test


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Evaluates a unique combination of 20 stool and serum measures all at 1 time for many common causes of persistent diarrhea.
Visit www.ibcause.com for detailed information.
PROMETHEUS IBcause Diagnostic<sup>®</sup>
IBD
PROMETHEUS®

7C4 Diagnostic Test


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7C4 Diagnostic Test
Measures 7α-hydroxy-4-cholesten-3-one (7C4) levels to help determine if bile acid malabsorption (BAM) may be the underlying cause of patients' gastrointestinal-related symptoms.

* Available in all states except New York (pending).
7C4 Diagnostic Test
PROMETHEUS®

Monitr™
Crohn's Disease


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Provides a unique combination of 13 biomarkers to assess mucosal healing in Crohn's disease (CD) patients.
Learn more about Monitr™.
PROMETHEUS Monitr
PROMETHEUS®

IBD sgi Diagnostic®


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IBD sgi Diagnostic®
Combines serologic, genetic, and inflammation markers to help differentiate IBD vs non-IBD and ulcerative colitis (UC) vs Crohn's disease (CD).
PROMETHEUS IBD sgi Diagnostic<sup>®</sup>
PROMETHEUS®

Crohn's Prognostic


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Crohn's Prognostic
Evaluate the probability of disease progression in a CD patient by providing a personal serogenetic profile.
Crohns Prognostic
BIOLOGIC
MONITORING
PROMETHEUS®

Anser® IFX



+ See more about Anser® IFX
Simultaneously measures infliximab (IFX) and antibodies to infliximab (ATI) levels in serum at any time during therapy. Can also be used with IFX biosimilars.
Visit www.anserifx.com for detailed information.
Anser-IFX
PROMETHEUS®

Anser® ADA



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Simultaneously measures adalimumab (ADA) and antibodies to adalimumab (ATA) levels in serum at any time during therapy.
Visit www.anserada.com for detailed information.
Anser-ADA
PROMETHEUS®

Anser® UST



Simultaneously measures ustekinumab (UST) and antibodies to ustekinumab (UST) levels in serum.
Visit www.anserust.com for detailed information.
Anser-UST
PROMETHEUS®

Anser® VDZ



+ See more about Anser® VDZ
Simultaneously measures vedolizumab (VDZ) and antibodies to vedolizumab (ATV) levels in serum at any time during therapy.
Visit www.anservdz.com for detailed information.
Anser-VDZ
CELIAC
PROMETHEUS®

Celiac Plus


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Celiac Plus
Combines serologic, genetic, and inflammation markers to help identify active celiac disease and stratify relative risk.
Visit www.celiacplus.com for detailed information.
Celiac
PROMETHEUS®

Celiac Genetics


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Celiac Genetics
Analyzes a patient's genetic profile for disease risk stratification.
PROMETHEUS®

Celiac Serology


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Celiac Serology
Comprehensive serum antibody profile combines 5 serological markers (IgG, IgA, tTG, EMA, and total serum IgA) for the diagnosis of celiac disease.
THIOPURINE
MANAGEMENT
PROMETHEUS®

TPMT Genetics


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TPMT Genetics
Genotypes a patient, allowing for individualized starting dose of thiopurines. Ordering prior to inititating therapy provides information for effective dosing, which may acheive maximum efficacy with minimized toxicity.
Thiopurine Testing
PROMETHEUS®

TPMT Enzyme


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TPMT Enzyme
Phenotypes a patient, allowing for individualized starting dose of thiopurines. Ordering prior to inititating therapy provides information for effective dosing, which may acheive maximum efficacy with minimized toxicity.
Thiopurine Testing
PROMETHEUS®

Thiopurine Metabolites


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Thiopurine Metabolites
Helps optimize ongoing dosing of thiopurines in order to reach and maintain a desired clinical response.
Thiopurine Monitoring
LIVER
PROMETHEUS®

FIBROSpect® HCV


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FIBROSpect® HCV
Noninvasively helps detect, stage, and monitor severity of liver fibrosis for hepatitus C virus (HCV) patients.
Learn more about FIBROSpect® HCV.
fibrospect
PROMETHEUS®

FIBROSpect® NASH


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FIBROSpect® NASH
Noninvasively helps detect, stage, and monitor severity of liver fibrosis for nonalcoholic steatohepatitus (NASH) patients.
Learn more about FIBROSpect® NASH.
fibrospect
OTHER
PROMETHEUS®

LactoTYPE®

Genetics test to help identify primary lactase nonpersistence.
PROMETHEUS®

NOD2/CARD15

For prognostic information in patients diagnosed with Crohn’s disease.
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